IL-24 Negatively Regulates Keratinocyte Differentiation Induced by Tapinarof, an Aryl Hydrocarbon Receptor Modulator: Implication in the Treatment of Atopic Dermatitis

Skin barrier dysfunction, including reduced filaggrin (FLG) and loricrin (LOR) expression, plays a critical role in atopic dermatitis (AD) development. Since aryl hydrocarbon receptor (AHR), a ligand-activated transcription factor, mediates keratinocyte differentiation, it is a potential target for...

Descripción completa

Detalles Bibliográficos
Autores principales: Vu, Yen Hai, Hashimoto-Hachiya, Akiko, Takemura, Masaki, Yumine, Ayako, Mitamura, Yasutaka, Nakahara, Takeshi, Furue, Masutaka, Tsuji, Gaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764126/
https://www.ncbi.nlm.nih.gov/pubmed/33321923
http://dx.doi.org/10.3390/ijms21249412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764126/
https://www.ncbi.nlm.nih.gov/pubmed/33321923
http://dx.doi.org/10.3390/ijms21249412

Ejemplares similares