The Failed Clinical Story of Myostatin Inhibitors against Duchenne Muscular Dystrophy: Exploring the Biology behind the Battle

Myostatin inhibition therapy has held much promise for the treatment of muscle wasting disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy (DMD). Following on from promising pre-clinical data in dystrophin-deficient mice and dogs, several clinical trials were ini...

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Detalles Bibliográficos
Autores principales: Rybalka, Emma, Timpani, Cara A., Debruin, Danielle A., Bagaric, Ryan M., Campelj, Dean G., Hayes, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764137/
https://www.ncbi.nlm.nih.gov/pubmed/33322031
http://dx.doi.org/10.3390/cells9122657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764137/
https://www.ncbi.nlm.nih.gov/pubmed/33322031
http://dx.doi.org/10.3390/cells9122657

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