Assessment of Tissue Distribution and Metabolism of MP1, a Novel Pyrrolomycin, in Mice Using a Validated LC-MS/MS Method

MP1 is a novel marinopyrrole analogue with activity in MYCN amplified neuroblastoma cell lines. A rapid, selective, and sensitive liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method was developed and validated for quantitation of MP1 in mouse plasma. Analyte separation was...

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Detalles Bibliográficos
Autores principales: Aldhafiri, Wafaa N., Chhonker, Yashpal S., Zhang, Yuning, Coutler, Don W., McGuire, Timothy R., Li, Rongshi, Murry, Daryl J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764159/
https://www.ncbi.nlm.nih.gov/pubmed/33322110
http://dx.doi.org/10.3390/molecules25245898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764159/
https://www.ncbi.nlm.nih.gov/pubmed/33322110
http://dx.doi.org/10.3390/molecules25245898

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