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UBAC1/KPC2 Regulates TLR3 Signaling in Human Keratinocytes through Functional Interaction with the CARD14/CARMA2sh-TANK Complex

CARD14/CARMA2 is a scaffold molecule whose genetic alterations are linked to human inherited inflammatory skin disorders. However, the mechanisms through which CARD14/CARMA2 controls innate immune response and chronic inflammation are not well understood. By means of a yeast two-hybrid screening, we...

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Detalles Bibliográficos
Autores principales: Mazzone, Pellegrino, Congestrì, Michele, Scudiero, Ivan, Polvere, Immacolata, Voccola, Serena, Zerillo, Lucrezia, Telesio, Gianluca, Vito, Pasquale, Stilo, Romania, Zotti, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764236/
https://www.ncbi.nlm.nih.gov/pubmed/33316896
http://dx.doi.org/10.3390/ijms21249365