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Toward Mechanistic Design of Surrogate Buffers for Dissolution Testing of pH-Dependent Drug Delivery Systems

The in vivo dissolution of enteric-coated (EC) products is often overestimated by compendial in vitro dissolution experiments. It is of great interest to mimic the in vivo conditions as closely as possible in vitro in order to predict the in vivo behavior of EC dosage forms. The reason behind this i...

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Detalles Bibliográficos
Autores principales: Blechar, Johannes Andreas, Al-Gousous, Jozef, Wilhelmy, Christoph, Postina, Annika Marielina, Getto, Marcus, Langguth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764239/
https://www.ncbi.nlm.nih.gov/pubmed/33321933
http://dx.doi.org/10.3390/pharmaceutics12121197