An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors

Botulinum toxins are neurotoxins produced by Clostridium botulinum. This toxin can be lethal for humans as a cause of botulism; however, in small doses, the same toxin is used to treat different conditions. Even if the therapeutic doses are effective and safe, the adverse reactions could be local an...

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Detalles Bibliográficos
Autores principales: Gentile, Davide, Floresta, Giuseppe, Patamia, Vincenzo, Chiaramonte, Rita, Mauro, Giulia Letizia, Rescifina, Antonio, Vecchio, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764241/
https://www.ncbi.nlm.nih.gov/pubmed/33322848
http://dx.doi.org/10.3390/ijms21249470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764241/
https://www.ncbi.nlm.nih.gov/pubmed/33322848
http://dx.doi.org/10.3390/ijms21249470

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