Widespread Aberrant Alternative Splicing despite Molecular Remission in Chronic Myeloid Leukaemia Patients

SIMPLE SUMMARY: This study provides new insights into the changing transcriptomic and epigenomic landscapes in chronic myeloid leukaemia (CML) patients who are receiving tyrosine kinase inhibitor (TKI) therapy (often life-long). Alternative splicing, vital for cellular homeostasis, is dysregulated i...

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Detalles Bibliográficos
Autores principales: Schmitz, Ulf, Shah, Jaynish S., Dhungel, Bijay P., Monteuuis, Geoffray, Luu, Phuc-Loi, Petrova, Veronika, Metierre, Cynthia, Nair, Shalima S., Bailey, Charles G., Saunders, Verity A., Turhan, Ali G., White, Deborah L., Branford, Susan, Clark, Susan J., Hughes, Timothy P., Wong, Justin J.-L., Rasko, John E.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764299/
https://www.ncbi.nlm.nih.gov/pubmed/33322625
http://dx.doi.org/10.3390/cancers12123738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764299/
https://www.ncbi.nlm.nih.gov/pubmed/33322625
http://dx.doi.org/10.3390/cancers12123738

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