Functional Dependency Analysis Identifies Potential Druggable Targets in Acute Myeloid Leukemia

SIMPLE SUMMARY: New drugs are needed for treating acute myeloid leukemia (AML). We analyzed data from genome-edited leukemia cells to identify druggable targets. These targets were necessary for AML cell survival and had favorable binding sites for drug development. Two lists of genes are provided f...

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Detalles Bibliográficos
Autores principales: Zhou, Yujia, Takacs, Gregory P., Lamba, Jatinder K., Vulpe, Christopher, Cogle, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764352/
https://www.ncbi.nlm.nih.gov/pubmed/33321907
http://dx.doi.org/10.3390/cancers12123710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764352/
https://www.ncbi.nlm.nih.gov/pubmed/33321907
http://dx.doi.org/10.3390/cancers12123710

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