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Differential Contribution of N- and C-Terminal Regions of HIF1α and HIF2α to Their Target Gene Selectivity

Cellular response to hypoxia is controlled by the hypoxia-inducible transcription factors HIF1α and HIF2α. Some genes are preferentially induced by HIF1α or HIF2α, as has been explored in some cell models and for particular sets of genes. Here we have extended this analysis to other HIF-dependent ge...

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Detalles Bibliográficos
Autores principales: Bouthelier, Antonio, Meléndez-Rodríguez, Florinda, Urrutia, Andrés A., Aragonés, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764359/
https://www.ncbi.nlm.nih.gov/pubmed/33321829
http://dx.doi.org/10.3390/ijms21249401