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Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2

SIMPLE SUMMARY: Cancers include a diverse collection of cells harboring distinct molecular signatures with different levels of pro-metastatic activities. This intratumoral heterogeneity and phenotypic plasticity are major causes of targeted therapeutic failure and it should be considered when develo...

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Detalles Bibliográficos
Autores principales: Sáenz-de-Santa-María, Inés, Celada, Lucía, San José Martínez, Andrés, Cubiella, Tamara, Chiara, María-Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764466/
https://www.ncbi.nlm.nih.gov/pubmed/33321813
http://dx.doi.org/10.3390/cancers12123708