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Changes in Ion Selectivity Following the Asymmetrical Addition of Charge to the Selectivity Filter of Bacterial Sodium Channels
Voltage-gated sodium channels (NaVs) play fundamental roles in eukaryotes, but their exceptional size hinders their structural resolution. Bacterial NaVs are simplified homologues of their eukaryotic counterparts, but their use as models of eukaryotic Na(+) channels is limited by their homotetrameri...
Autores principales: | Fedorenko, Olena A., Khovanov, Igor A., Roberts, Stephen K., Guardiani, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764494/ https://www.ncbi.nlm.nih.gov/pubmed/33316962 http://dx.doi.org/10.3390/e22121390 |
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