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Near haploidization is a genomic hallmark which defines a molecular subgroup of giant cell glioblastoma

BACKGROUND: Giant cell glioblastoma (gcGBM) is a rare histologic subtype of glioblastoma characterized by numerous bizarre multinucleate giant cells and increased reticulin deposition. Compared with conventional isocitrate dehydrogenase (IDH)-wildtype glioblastomas, gcGBMs typically occur in younger...

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Detalles Bibliográficos
Autores principales: Baker, Tiffany G, Alden, Jay, Dubuc, Adrian M, Welsh, Cynthia T, Znoyko, Iya, Cooley, Linda D, Farooqi, Midhat S, Schwartz, Stuart, Li, Yvonne Y, Cherniack, Andrew D, Lindhorst, Scott M, Gener, Melissa, Wolff, Daynna J, Meredith, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764500/
https://www.ncbi.nlm.nih.gov/pubmed/33392505
http://dx.doi.org/10.1093/noajnl/vdaa155