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A GSH-Responsive Nanoprodrug System Based on Self-Assembly of Lactose Modified Camptothecin for Targeted Drug Delivery and Combination Chemotherapy

BACKGROUND: Conventional chemotherapy using small molecular antitumor drugs suffers from several limitations, for instance poor water solubility, high toxicity, and lack of specificity. However, prodrugs constructed by covalent modification of anticancer drugs can overcome these limitations, which a...

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Detalles Bibliográficos
Autores principales: Hou, Chenxi, Ma, Ning, Shen, Ziyan, Chi, Guanyu, Chao, Shuang, Pei, Yuxin, Chen, Lan, Lu, Yuchao, Pei, Zhichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764549/
https://www.ncbi.nlm.nih.gov/pubmed/33376329
http://dx.doi.org/10.2147/IJN.S276470