Cargando…

A GSH-Responsive Nanoprodrug System Based on Self-Assembly of Lactose Modified Camptothecin for Targeted Drug Delivery and Combination Chemotherapy

BACKGROUND: Conventional chemotherapy using small molecular antitumor drugs suffers from several limitations, for instance poor water solubility, high toxicity, and lack of specificity. However, prodrugs constructed by covalent modification of anticancer drugs can overcome these limitations, which a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hou, Chenxi, Ma, Ning, Shen, Ziyan, Chi, Guanyu, Chao, Shuang, Pei, Yuxin, Chen, Lan, Lu, Yuchao, Pei, Zhichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764549/ https://www.ncbi.nlm.nih.gov/pubmed/33376329 http://dx.doi.org/10.2147/IJN.S276470

Ejemplares similares

Indocyanine green potentiated paclitaxel nanoprodrugs for imaging and chemotherapy
por: Xiang, Xiujuan, et al.
Publicado: (2022)

Nanoprodrugs of NSAIDs: Preparation and Characterization of Flufenamic Acid Nanoprodrugs
por: Lee, Bong-Seop, et al.
Publicado: (2011)

Hydrophilic Fluorescent Nanoprodrug of Paclitaxel for Glioblastoma Chemotherapy
por: Daniel, Jonathan, et al.
Publicado: (2019)

Glyconanoparticles with Activatable Near-Infrared Probes for Tumor-Cell Imaging and Targeted Drug Delivery
por: Chi, Guanyu, et al.
Publicado: (2022)

A redox-responsive dihydroartemisinin dimeric nanoprodrug for enhanced antitumor activity
por: Li, Yawei, et al.
Publicado: (2021)

Self-Assembled Silk Fibroin-Based Aggregates for Delivery of Camptothecin
por: Pérez Quiñones, Javier, et al.
Publicado: (2021)

A multifunctional supramolecular vesicle based on complex of cystamine dihydrochloride capped pillar[5]arene and galactose derivative for targeted drug delivery
por: Lu, Yuchao, et al.
Publicado: (2019)

Supramolecular Vesicles Based on Amphiphilic Pillar[n]arenes for Smart Nano-Drug Delivery
por: Hua, Yijie, et al.
Publicado: (2020)

Camptothecin-based nanodrug delivery systems
por: Wen, Yan, et al.
Publicado: (2017)

Acetaldehyde-modified-cystine functionalized Zr-MOFs for pH/GSH dual-responsive drug delivery and selective visualization of GSH in living cells
por: Lin, Caixue, et al.
Publicado: (2020)

Silica nanoparticle-based dual-responsive nanoprodrug system for liver cancer therapy
por: Xia, Qing, et al.
Publicado: (2017)

Salinomycin-Loaded Small-Molecule Nanoprodrugs Enhance Anticancer Activity in Hepatocellular Carcinoma
por: Wang, Jianguo, et al.
Publicado: (2020)

An erythrocyte-delivered photoactivatable oxaliplatin nanoprodrug for enhanced antitumor efficacy and immune response
por: Wang, Na, et al.
Publicado: (2021)

The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma
por: Xu, Haoyue, et al.
Publicado: (2022)

Intranasal Delivery of Camptothecin-Loaded Tat-Modified Nanomicells for Treatment of Intracranial Brain Tumors
por: Taki, Hiroyuki, et al.
Publicado: (2012)

Carrier-free nanoprodrug for p53-mutated tumor therapy via concurrent delivery of zinc-manganese dual ions and ROS
por: Wang, Jinping, et al.
Publicado: (2022)

Reactive Oxygen Species-Activated Nanoprodrug of Ibuprofen for Targeting Traumatic Brain Injury in Mice
por: Clond, Morgan A., et al.
Publicado: (2013)

Regioselective Benzoylation of Diols and Carbohydrates by Catalytic Amounts of Organobase
por: Lu, Yuchao, et al.
Publicado: (2016)

Efficient GSH delivery using PAMAM-GSH into MPP-induced PC12 cellular model for Parkinson’s disease
por: Sun, Hong-Ji, et al.
Publicado: (2016)

Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy
por: Li, Zekun, et al.
Publicado: (2022)

Binary Solutions of Hyaluronan and Lactose-Modified Chitosan: The Influence of Experimental Variables in Assembling Complex Coacervates
por: Vecchies, Federica, et al.
Publicado: (2020)

Characterization of DNA Topoisomerase-1 in Spodoptera exigua for Toxicity Evaluation of Camptothecin and Hydoxy-Camptothecin
por: Zhang, Lan, et al.
Publicado: (2013)

Lactose Sensitivity and Lactose Malabsorption: The 2 Faces of Lactose Intolerance
por: Bouchoucha, Michel, et al.
Publicado: (2021)

An orthogonally activatable CRISPR-Cas13d nanoprodrug to reverse chemoresistance for enhanced chemo-photodynamic therapy
por: Liu, Zheng, et al.
Publicado: (2023)

Influence of Pasteurization on Maillard Reaction in Lactose-Free Milk
por: Bi, Haixin, et al.
Publicado: (2023)

Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin
por: Huarte, Judit, et al.
Publicado: (2021)

Self-defensive nano-assemblies from camptothecin-based antitumor drugs
por: Qin, Si-Yong, et al.
Publicado: (2015)

Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin
por: Pusuluri, Anusha, et al.
Publicado: (2019)

Dual-responsive dithio-polydopamine coated porous CeO(2) nanorods for targeted and synergistic drug delivery
por: Zhang, Ying, et al.
Publicado: (2018)

Recent Advances in the Treatment of Neurodegenerative Diseases Based on GSH Delivery Systems
por: Cacciatore, Ivana, et al.
Publicado: (2012)

Cyclodextrin nanosponge for the GSH-mediated delivery of Resveratrol in human cancer cells
por: Palminteri, Marco, et al.
Publicado: (2021)

Functional re-evaluation of the putative glutathione transporters, RcGshT and RsGshT.
por: Li, L., et al.
Publicado: (1997)

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system
por: Castillo, Paula M, et al.
Publicado: (2014)

Mitochondria-Targeted Delivery of Camptothecin Based on HPMA Copolymer for Metastasis Suppression
por: Yi, Xiaoli, et al.
Publicado: (2022)

A Universal Photochemical Method to Prepare Carbohydrate Sensors Based on Perfluorophenylazide Modified Polydopamine for Study of Carbohydrate-Lectin Interactions by QCM Biosensor
por: Guo, Lili, et al.
Publicado: (2019)

Prostate-Specific Membrane Antigen and Esterase Dual Responsive Camptothecin–Oligopeptide Self-Assembled Nanoparticles for Efficient Anticancer Drug Delivery
por: Xu, Bing, et al.
Publicado: (2021)

In Situ Encapsulation of Camptothecin by Self-Assembly of Poly(acrylic acid)-b-Poly(N-Isopropylacrylamide) and Chitosan for Controlled Drug Delivery
por: Huang, Yi-Cheng, et al.
Publicado: (2023)

GSH-Activatable Metal-Phenolic Networks for Photothermal-Enhanced Chemotherapy and Chemodynamic Therapy
por: Chen, Weijun, et al.
Publicado: (2023)

Chromosome-level genome assembly of Ophiorrhiza pumila reveals the evolution of camptothecin biosynthesis
por: Rai, Amit, et al.
Publicado: (2021)

Microenvironment Activatable Nanoprodrug Based on Gripper-like Cyclic Phenylboronic Acid to Precisely and Effectively Alleviate Drug-induced Hepatitis
por: Zhang, Qixiong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ph570ph6nhjifrps5jru2724bj