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Acute Myeloid Leukemia Stem Cells: The Challenges of Phenotypic Heterogeneity

SIMPLE SUMMARY: Relapse after apparent remission remains a major cause of death in patients with acute myeloid leukemia (AML). On the cellular level, leukemia relapse is considered to emerge from subpopulations of therapy-resistant leukemic stem cells (LSC). Identification and targeting of LSC are t...

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Detalles Bibliográficos
Autores principales: Arnone, Marlon, Konantz, Martina, Hanns, Pauline, Paczulla Stanger, Anna M., Bertels, Sarah, Godavarthy, Parimala Sonika, Christopeit, Maximilian, Lengerke, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764578/
https://www.ncbi.nlm.nih.gov/pubmed/33322769
http://dx.doi.org/10.3390/cancers12123742