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Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis

SIMPLE SUMMARY: In vitro models able to represent osteoarthritis (OA) synovial tissue (ST) inflammation are lacking. Therefore, we aimed to characterize OA ST and to compare mechanical and enzymatic digestion procedures to find the one that better preserve the heterogeneity of the main OA synovial c...

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Detalles Bibliográficos
Autores principales: Manferdini, Cristina, Saleh, Yasmin, Dolzani, Paolo, Gabusi, Elena, Trucco, Diego, Filardo, Giuseppe, Lisignoli, Gina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764613/
https://www.ncbi.nlm.nih.gov/pubmed/33321965
http://dx.doi.org/10.3390/biology9120459