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Stem Cell-Derived Exosomes Ameliorate Doxorubicin-Induced Muscle Toxicity through Counteracting Pyroptosis

Doxorubicin (Dox)-induced muscle toxicity (DIMT) is a common occurrence in cancer patients; however, the cause of its development and progression is not established. We tested whether inflammation-triggered cell death, “pyroptosis” plays a role in DIMT. We also examined the potential role of exosome...

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Detalles Bibliográficos
Autores principales: Dessouki, Fatima Bianca A., Kukreja, Rakesh C., Singla, Dinender K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764639/
https://www.ncbi.nlm.nih.gov/pubmed/33316945
http://dx.doi.org/10.3390/ph13120450