Transferrin-Bound Doxorubicin Enhances Apoptosis and DNA Damage through the Generation of Pro-Inflammatory Responses in Human Leukemia Cells

Doxorubicin (DOX) is an effective antineoplastic drug against many solid tumors and hematological malignancies. However, the clinical use of DOX is limited, because of its unspecific mode of action. Since leukemia cells overexpress transferrin (Tf) receptors on their surface, we proposed doxorubicin...

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Detalles Bibliográficos
Autores principales: Jedrzejczyk, Monika, Wisniewska, Katarzyna, Kania, Katarzyna Dominika, Marczak, Agnieszka, Szwed, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764702/
https://www.ncbi.nlm.nih.gov/pubmed/33321722
http://dx.doi.org/10.3390/ijms21249390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764702/
https://www.ncbi.nlm.nih.gov/pubmed/33321722
http://dx.doi.org/10.3390/ijms21249390

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