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Impact of BRCA Mutation Status on Tumor Infiltrating Lymphocytes (TILs), Response to Treatment, and Prognosis in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy

SIMPLE SUMMARY: High lymphocytic infiltration (TILs) seem to reflect favorable host antitumor immune responses. In breast cancer, the variation of TILs before and after neoadjuvant chemotherapy (NAC) according to BRCA status has been poorly described. Little data is available on their value after tr...

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Detalles Bibliográficos
Autores principales: Grandal, Beatriz, Evrevin, Clémence, Laas, Enora, Jardin, Isabelle, Rozette, Sonia, Laot, Lucie, Dumas, Elise, Coussy, Florence, Pierga, Jean-Yves, Brain, Etienne, Saule, Claire, Stoppa-Lyonnet, Dominique, Frank, Sophie, Sénéchal, Claire, Lae, Marick, De Croze, Diane, Bataillon, Guillaume, Guerin, Julien, Reyal, Fabien, Hamy, Anne-Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764707/
https://www.ncbi.nlm.nih.gov/pubmed/33302444
http://dx.doi.org/10.3390/cancers12123681