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Regulation of Oncogenic Targets by the Tumor-Suppressive miR-139 Duplex (miR-139-5p and miR-139-3p) in Renal Cell Carcinoma

We previously found that both the guide and passenger strands of the miR-139 duplex (miR-139-5p and miR-139-3p, respectively) were downregulated in cancer tissues. Analysis of TCGA datasets revealed that low expression of miR-139-5p (p < 0.0001) and miR-139-3p (p < 0.0001) was closely associat...

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Detalles Bibliográficos
Autores principales: Okada, Reona, Goto, Yusuke, Yamada, Yasutaka, Kato, Mayuko, Asai, Shunichi, Moriya, Shogo, Ichikawa, Tomohiko, Seki, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764717/
https://www.ncbi.nlm.nih.gov/pubmed/33322675
http://dx.doi.org/10.3390/biomedicines8120599