Molecular Insights into Determinants of Translational Readthrough and Implications for Nonsense Suppression Approaches

The fidelity of protein synthesis, a process shaped by several mechanisms involving specialized ribosome regions and external factors, ensures the precise reading of sense and stop codons. However, premature termination codons (PTCs) arising from mutations may, at low frequency, be misrecognized and...

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Detalles Bibliográficos
Autores principales: Lombardi, Silvia, Testa, Maria Francesca, Pinotti, Mirko, Branchini, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764779/
https://www.ncbi.nlm.nih.gov/pubmed/33322589
http://dx.doi.org/10.3390/ijms21249449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764779/
https://www.ncbi.nlm.nih.gov/pubmed/33322589
http://dx.doi.org/10.3390/ijms21249449

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