Implication of Lactucopicrin in Autophagy, Cell Cycle Arrest and Oxidative Stress to Inhibit U87Mg Glioblastoma Cell Growth

In this study, we propose lactucopicrin (LCTP), a natural sesquiterpene lactone from Lactucavirosa, as a molecule able to control the growth of glioblastoma continuous cell line U87Mg. The IC50 of U87Mg against LCTP revealed a strong cytotoxic effect. Daily administration of LCTP showed a dose and t...

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Detalles Bibliográficos
Autores principales: Rotondo, Rossella, Oliva, Maria Antonietta, Staffieri, Sabrina, Castaldo, Salvatore, Giangaspero, Felice, Arcella, Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764785/
https://www.ncbi.nlm.nih.gov/pubmed/33322048
http://dx.doi.org/10.3390/molecules25245843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764785/
https://www.ncbi.nlm.nih.gov/pubmed/33322048
http://dx.doi.org/10.3390/molecules25245843

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