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Implication of Lactucopicrin in Autophagy, Cell Cycle Arrest and Oxidative Stress to Inhibit U87Mg Glioblastoma Cell Growth

In this study, we propose lactucopicrin (LCTP), a natural sesquiterpene lactone from Lactucavirosa, as a molecule able to control the growth of glioblastoma continuous cell line U87Mg. The IC50 of U87Mg against LCTP revealed a strong cytotoxic effect. Daily administration of LCTP showed a dose and t...

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Detalles Bibliográficos
Autores principales:	Rotondo, Rossella, Oliva, Maria Antonietta, Staffieri, Sabrina, Castaldo, Salvatore, Giangaspero, Felice, Arcella, Antonietta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764785/ https://www.ncbi.nlm.nih.gov/pubmed/33322048 http://dx.doi.org/10.3390/molecules25245843

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