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Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs

Multivalent antibody constructs have a broad range of clinical and biotechnological applications. Nanobodies are especially useful as components for multivalent constructs as they allow increased valency while maintaining a small molecule size. We here describe a novel, rapid method for the generati...

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Detalles Bibliográficos
Autores principales: Moliner-Morro, Ainhoa, J. Sheward, Daniel, Karl, Vivien, Perez Vidakovics, Laura, Murrell, Ben, McInerney, Gerald M., Hanke, Leo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764822/
https://www.ncbi.nlm.nih.gov/pubmed/33322557
http://dx.doi.org/10.3390/biom10121661