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Effects of the Glass-Forming Ability and Annealing Conditions on Cocrystallization Behaviors via Rapid Solvent Removal: A Case Study of Voriconazole

The kinetic entrapment of molecules in an amorphous phase is a common obstacle to cocrystal screening using rapid solvent removal, especially for drugs with a moderate or high glass-forming ability (GFA). The aim of this study was to elucidate the effects of the coformer’s GFA and annealing conditio...

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Detalles Bibliográficos
Autores principales: Wong, Si Nga, Chan, Susan Wing Sze, Peng, Xuexin, Xuan, Bianfei, Lee, Hok Wai, Tong, Henry H. Y., Chow, Shing Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764899/
https://www.ncbi.nlm.nih.gov/pubmed/33327381
http://dx.doi.org/10.3390/pharmaceutics12121209