Germline TP53 Testing in Breast Cancers: Why, When and How?

SIMPLE SUMMARY: TP53 variants detected in blood represent a main genetic cause of breast cancers occurring before 31 years of age. TP53 being included in most of the cancer gene panels, patients with breast cancer are offered germline TP53 testing, independently of the age of tumour onset and famili...

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Detalles Bibliográficos
Autores principales: Evans, D. Gareth, Woodward, Emma R., Bajalica-Lagercrantz, Svetlana, Oliveira, Carla, Frebourg, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764913/
https://www.ncbi.nlm.nih.gov/pubmed/33327514
http://dx.doi.org/10.3390/cancers12123762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764913/
https://www.ncbi.nlm.nih.gov/pubmed/33327514
http://dx.doi.org/10.3390/cancers12123762

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