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Conformation of the Intermediates in the Reaction Catalyzed by Protoporphyrinogen Oxidase: An In Silico Analysis

Protoporphyrinogen oxidase (PPO) is a critical enzyme across life as the last common step in the synthesis of many metalloporphyrins. The reaction mechanism of PPO was assessed in silico and the unstructured loop near the binding pocket was investigated. The substrate, intermediates, and product wer...

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Detalles Bibliográficos
Autores principales: Barker, Abigail L., Barnes, Hamlin, Dayan, Franck E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764921/
https://www.ncbi.nlm.nih.gov/pubmed/33327448
http://dx.doi.org/10.3390/ijms21249495