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TAK1 Mediates ROS Generation Triggered by the Specific Cephalosporins through Noncanonical Mechanisms

It is known that a wide variety of antibacterial agents stimulate generation of reactive oxygen species (ROS) in mammalian cells. However, its mechanisms are largely unknown. In this study, we unexpectedly found that transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) is involved in the g...

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Detalles Bibliográficos
Autores principales: Suzuki, Midori, Asai, Yukino, Kagi, Tomohiro, Noguchi, Takuya, Yamada, Mayuka, Hirata, Yusuke, Matsuzawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764951/
https://www.ncbi.nlm.nih.gov/pubmed/33327477
http://dx.doi.org/10.3390/ijms21249497