MEK1 Inhibitor Combined with Irradiation Reduces Migration of Breast Cancer Cells Including miR-221 and ZEB1 EMT Marker Expression

SIMPLE SUMMARY: Combined chemotherapy and radiotherapy are an effective treatment for invasive breast cancer. However, some studies suggest that such interventions may increase the risk of metastasis. Cell metastatic behavior is highly dependent on RAS-RAF-MEK pathway and its downstream target activ...

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Detalles Bibliográficos
Autores principales: Anastasov, Nataša, Hirmer, Elisabeth, Klenner, Marbod, Ott, Jessica, Falkenberg, Natalie, Bao, Xuanwen, Mutschelknaus, Lisa, Moertl, Simone, Combs, Stephanie, Atkinson, Michael J., Schmid, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764972/
https://www.ncbi.nlm.nih.gov/pubmed/33327491
http://dx.doi.org/10.3390/cancers12123760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764972/
https://www.ncbi.nlm.nih.gov/pubmed/33327491
http://dx.doi.org/10.3390/cancers12123760

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