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P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus

p27(Kip1) (p27), a well-known cell regulator, is involved in the regulation of cell death and survival. In the present study, we observed the effects of p27 against oxidative stress induced by H(2)O(2) in HT22 cells and transient ischemia in gerbils. Tat (trans-acting activator of transcription) pep...

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Detalles Bibliográficos
Autores principales: Kim, Woosuk, Kwon, Hyun Jung, Jung, Hyo Young, Hahn, Kyu Ri, Yoon, Yeo Sung, Hwang, In Koo, Choi, Soo Young, Kim, Dae Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764997/
https://www.ncbi.nlm.nih.gov/pubmed/33327462
http://dx.doi.org/10.3390/ijms21249496