Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice

Emerging evidence suggests that epigenetic mechanisms such as histone modification are crucially involved in the pathophysiology of acute kidney injury (AKI). The histone acetyltransferase p300 regulates several biological processes through the acetylation of histones or transcription factors. Howev...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Yeon, Jo, Jungmin, Leem, Jaechan, Park, Kwan-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765028/
https://www.ncbi.nlm.nih.gov/pubmed/33327548
http://dx.doi.org/10.3390/antiox9121271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765028/
https://www.ncbi.nlm.nih.gov/pubmed/33327548
http://dx.doi.org/10.3390/antiox9121271

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