Stereoselective Synthesis of Multisubstituted Cyclohexanes by Reaction of Conjugated Enynones with Malononitrile in the Presence of LDA

Reaction of linear conjugated enynones, 1,5-diarylpent-2-en-4-yn-1-ones, with malononitrile in the presence of lithium diisopropylamide LDA, as a base, in THF at room temperature for 3–7 h resulted in the formation of the product of dimerization, multisubstituted polyfunctional cyclohexanes, 4-aryl-...

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Detalles Bibliográficos
Autores principales: Igushkina, Anastasiya V., Golovanov, Alexander A., Boyarskaya, Irina A., Kolesnikov, Ilya E., Vasilyev, Aleksander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765106/
https://www.ncbi.nlm.nih.gov/pubmed/33327655
http://dx.doi.org/10.3390/molecules25245920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765106/
https://www.ncbi.nlm.nih.gov/pubmed/33327655
http://dx.doi.org/10.3390/molecules25245920

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