Cyano Enone-Bearing Triterpenoid Soloxolone Methyl Inhibits Epithelial-Mesenchymal Transition of Human Lung Adenocarcinoma Cells In Vitro and Metastasis of Murine Melanoma In Vivo

Introduction of α-cyano α,β-unsaturated carbonyl moiety into natural cyclic compounds markedly improves their bioactivities, including inhibitory potential against tumor growth and metastasis. Previously, we showed that cyano enone-bearing derivatives of 18βH-glycyrrhetinic (GA) and deoxycholic acid...

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Detalles Bibliográficos
Autores principales: Markov, Andrey V., Odarenko, Kirill V., Sen’kova, Aleksandra V., Salomatina, Oksana V., Salakhutdinov, Nariman F., Zenkova, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765109/
https://www.ncbi.nlm.nih.gov/pubmed/33327637
http://dx.doi.org/10.3390/molecules25245925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765109/
https://www.ncbi.nlm.nih.gov/pubmed/33327637
http://dx.doi.org/10.3390/molecules25245925

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