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Lipid-Iron Nanoparticle with a Cell Stress Release Mechanism Combined with a Local Alternating Magnetic Field Enables Site-Activated Drug Release

SIMPLE SUMMARY: A novel active release system magnetic sphingomyelin-containing liposome encapsulated with indocyanine green, fluorescent marker, or the anticancer drug cisplatin was evaluated. The liposomal sphingomyelin is a target for the sphingomyelinase enzyme, which is released by stressed cel...

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Detalles Bibliográficos
Autores principales: Peñate Medina, Tuula, Gerle, Mirko, Humbert, Jana, Chu, Hanwen, Köpnick, Anna-Lena, Barkmann, Reinhard, Garamus, Vasil M., Sanz, Beatriz, Purcz, Nicolai, Will, Olga, Appold, Lia, Damm, Timo, Suojanen, Juho, Arnold, Philipp, Lucius, Ralph, Willumeit-Römer, Regina, Açil, Yahya, Wiltfang, Joerg, Goya, Gerardo F., Glüer, Claus C., Peñate Medina, Oula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765112/
https://www.ncbi.nlm.nih.gov/pubmed/33327621
http://dx.doi.org/10.3390/cancers12123767