Synthesis, Structure and Cytotoxicity Testing of Novel 7-(4,5-Dihydro-1H-imidazol-2-yl)-2-aryl-6,7-dihydro-2H-imidazo[2,1-c][1,2,4]triazol-3(5H)-Imine Derivatives

The appropriate 1-arylhydrazinecarbonitriles 1a–c are subjected to the reaction with 2-chloro-4,5-dihydro-1H-imidazole (2), yielding 7-(4,5-dihydro-1H-imidazol-2-yl)-2-aryl-6,7-dihydro-2H-imidazo[2,1-c][1,2,4]triazol-3(5H)-imines 3a–c, which are subsequently converted into the corresponding amides 4...

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Detalles Bibliográficos
Autores principales: Balewski, Łukasz, Sączewski, Franciszek, Bednarski, Patrick J., Wolff, Lisa, Nadworska, Anna, Gdaniec, Maria, Kornicka, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765142/
https://www.ncbi.nlm.nih.gov/pubmed/33327611
http://dx.doi.org/10.3390/molecules25245924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765142/
https://www.ncbi.nlm.nih.gov/pubmed/33327611
http://dx.doi.org/10.3390/molecules25245924

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