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Analytical Methods for the Detection and Quantification of ADCs in Biological Matrices

Understanding pharmacokinetics and biodistribution of antibody–drug conjugates (ADCs) is a one of the critical steps enabling their successful development and optimization. Their complex structure combining large and small molecule characteristics brought out multiple bioanalytical methods to deciph...

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Detalles Bibliográficos
Autores principales: Cahuzac, Héloïse, Devel, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765153/
https://www.ncbi.nlm.nih.gov/pubmed/33327644
http://dx.doi.org/10.3390/ph13120462