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Pathogenic Genome Signatures That Damage Motor Neurons in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease and a neurodegenerative disorder, affecting the upper and/or lower motor neurons. Notably, it invariably leads to death within a few years of onset. Although most ALS cases are sporadic, familial amyotrophic lateral sclero...

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Detalles Bibliográficos
Autores principales: Yousefian-Jazi, Ali, Seol, YunHee, Kim, Jieun, Ryu, Hannah L., Lee, Junghee, Ryu, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765192/
https://www.ncbi.nlm.nih.gov/pubmed/33333804
http://dx.doi.org/10.3390/cells9122687