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Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

Broadly neutralizing antibodies (bnAbs) isolated from HIV-infected individuals delineate vulnerable sites on the HIV envelope glycoprotein that are potential vaccine targets. A linear epitope within the N-terminal region of the HIV-1 fusion peptide (FP8) is the primary target of VRC34.01, a bnAb tha...

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Detalles Bibliográficos
Autores principales: Mogus, Alemu Tekewe, Liu, Lihong, Jia, Manxue, Ajayi, Diane T., Xu, Kai, Kong, Rui, Huang, Jing, Yu, Jian, Kwong, Peter D., Mascola, John R., Ho, David D., Tsuji, Moriya, Chackerian, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765226/
https://www.ncbi.nlm.nih.gov/pubmed/33333740
http://dx.doi.org/10.3390/vaccines8040765