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Rheological and Drug Delivery Characteristics of Poloxamer-Based Diclofenac Sodium Formulations for Chronic Wound Site Analgesia

Chronic wounds are a significant and growing health problem, and clinical treatment is often a painful experience. A topical dosage form would be optimal to treat this pain. Poloxamer 407, a thermosensitive polymer that is a liquid at low temperatures but gels at higher temperatures, is well suited...

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Detalles Bibliográficos
Autores principales: Russo, Jackson, Fiegel, Jennifer, Brogden, Nicole K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765230/
https://www.ncbi.nlm.nih.gov/pubmed/33333773
http://dx.doi.org/10.3390/pharmaceutics12121214