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Solid Lipid Curcumin Particles Protect Medium Spiny Neuronal Morphology, and Reduce Learning and Memory Deficits in the YAC128 Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is a genetic neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by massive neuronal degeneration in the striatum. In this study, we utilized solid lipid curcumin particles (SLCPs) and solid lipid particles (SLPs) to test thei...

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Detalles Bibliográficos
Autores principales: Gharaibeh, Abeer, Maiti, Panchanan, Culver, Rebecca, Heileman, Shiela, Srinageshwar, Bhairavi, Story, Darren, Spelde, Kristin, Paladugu, Leela, Munro, Nikolas, Muhn, Nathan, Kolli, Nivya, Rossignol, Julien, Dunbar, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765279/
https://www.ncbi.nlm.nih.gov/pubmed/33333883
http://dx.doi.org/10.3390/ijms21249542