EGFR-Binding Peptides: From Computational Design towards Tumor-Targeting of Adeno-Associated Virus Capsids

The epidermal growth factor receptor (EGFR) plays a central role in the progression of many solid tumors. We used this validated target to analyze the de novo design of EGFR-binding peptides and their application for the delivery of complex payloads via rational design of a viral vector. Peptides we...

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Detalles Bibliográficos
Autores principales: Feiner, Rebecca C., Kemker, Isabell, Krutzke, Lea, Allmendinger, Ellen, Mandell, Daniel J., Sewald, Norbert, Kochanek, Stefan, Müller, Kristian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765298/
https://www.ncbi.nlm.nih.gov/pubmed/33333826
http://dx.doi.org/10.3390/ijms21249535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765298/
https://www.ncbi.nlm.nih.gov/pubmed/33333826
http://dx.doi.org/10.3390/ijms21249535

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