Novel Thiosemicarbazones Sensitize Pediatric Solid Tumor Cell-Types to Conventional Chemotherapeutics through Multiple Molecular Mechanisms

SIMPLE SUMMARY: Combination of chemotherapeutics for the treatment of childhood cancer can lead to the use of lower cytotoxic drug doses and better therapeutic tolerability (i.e., lower side effects) for patients. We discovered novel molecular targets of two lead thiosemicarbazone agents of the di-2...

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Detalles Bibliográficos
Autores principales: Paukovcekova, Silvia, Skoda, Jan, Neradil, Jakub, Mikulenkova, Erika, Chlapek, Petr, Sterba, Jaroslav, Richardson, Des R., Veselska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765366/
https://www.ncbi.nlm.nih.gov/pubmed/33334021
http://dx.doi.org/10.3390/cancers12123781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765366/
https://www.ncbi.nlm.nih.gov/pubmed/33334021
http://dx.doi.org/10.3390/cancers12123781

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