Synthesis and In Vitro Antiprotozoan Evaluation of 4-/8-Aminoquinoline-based Lactams and Tetrazoles

A second generation of 4-aminoquinoline- and 8-aminoquinoline-based tetrazoles and lactams were synthesized via the Staudinger and Ugi multicomponent reactions. These compounds were subsequently evaluated in vitro for their potential antiplasmodium activity against a multidrug-resistant K1 strain an...

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Detalles Bibliográficos
Autores principales: Tukulula, Matshawandile, Louw, Stefan, Njoroge, Mathew, Chibale, Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765388/
https://www.ncbi.nlm.nih.gov/pubmed/33333924
http://dx.doi.org/10.3390/molecules25245941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765388/
https://www.ncbi.nlm.nih.gov/pubmed/33333924
http://dx.doi.org/10.3390/molecules25245941

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