Antiproliferative and Antiangiogenic Properties of New VEGFR-2-targeting 2-thioxobenzo[g]quinazoline Derivatives (In Vitro)

A series of 3-ethyl(methyl)-2-thioxo-2,3-dihydrobenzo[g]quinazolines (1–17) were synthesized, characterized, and evaluated in vitro for their antiangiogenesis VEGFR-2-targeting, antiproliferative, and antiapoptotic activities against breast MCF-7 and liver HepG2 cells. Flow cytometry was used to det...

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Detalles Bibliográficos
Autores principales: Abuelizz, Hatem A., Marzouk, Mohamed, Bakheit, Ahmed H., Awad, Hanem M., Soltan, Maha M., Naglah, Ahmed M., Al-Salahi, Rashad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765401/
https://www.ncbi.nlm.nih.gov/pubmed/33333992
http://dx.doi.org/10.3390/molecules25245944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765401/
https://www.ncbi.nlm.nih.gov/pubmed/33333992
http://dx.doi.org/10.3390/molecules25245944

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