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A Reliable Enantioselective Route to Mono-Protected N1-Cbz Piperazic Acid Building Block

The chiral N1-Cbz, N2-H derivative of the piperazic acid monomer is a valuable building block in the total synthesis of natural products, comprising this nonproteinogenic amino acid. In that context, we wish to report an improved synthetic protocol for the synthesis of both (3R)- and (3S)-piperazic...

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Detalles Bibliográficos
Autores principales: Papadaki, Evanthia, Georgiadis, Dimitris, Tsakos, Michail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765410/
https://www.ncbi.nlm.nih.gov/pubmed/33333919
http://dx.doi.org/10.3390/molecules25245939