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Tyrosine Phosphorylation of the K(v)2.1 Channel Contributes to Injury in Brain Ischemia

In brain ischemia, oxidative stress induces neuronal apoptosis, which is mediated by increased activity of the voltage-gated K(+) channel K(v)2.1 and results in an efflux of intracellular K(+). The molecular mechanisms underlying the regulation of K(v)2.1 and its activity during brain ischemia are n...

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Detalles Bibliográficos
Autores principales: Song, Min-Young, Hwang, Ji Yeon, Bae, Eun Ji, Kim, Saesbyeol, Kang, Hye-Min, Kim, Yong Jun, Park, Chan, Park, Kang-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765428/
https://www.ncbi.nlm.nih.gov/pubmed/33333928
http://dx.doi.org/10.3390/ijms21249538