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Siderophore Scaffold as Carrier for Antifungal Peptides in Therapy of Aspergillus fumigatus Infections

Antifungal resistance of human fungal pathogens represents an increasing challenge in modern medicine. Short antimicrobial peptides (AMP) display a promising class of antifungals with a different mode of action, but lack target specificity and metabolic stability. In this study the hexapeptide PAF26...

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Detalles Bibliográficos
Autores principales: Pfister, Joachim, Bata, Roland, Hubmann, Isabella, Hörmann, Anton Amadeus, Gsaller, Fabio, Haas, Hubertus, Decristoforo, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765500/
https://www.ncbi.nlm.nih.gov/pubmed/33334084
http://dx.doi.org/10.3390/jof6040367