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Engineering of Doxorubicin-Encapsulating and TRAIL-Conjugated Poly(RGD) Proteinoid Nanocapsules for Drug Delivery Applications

Proteinoids are non-toxic biodegradable polymers prepared by thermal step-growth polymerization of amino acids. Here, P(RGD) proteinoids and proteinoid nanocapsules (NCs) based on D-arginine, glycine, and L-aspartic acid were synthesized and characterized for targeted tumor therapy. Doxorubicin (Dox...

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Detalles Bibliográficos
Autores principales: Hadad, Elad, Rudnick-Glick, Safra, Itzhaki, Ella, Avivi, Matan Y., Grinberg, Igor, Elias, Yuval, Margel, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765502/
https://www.ncbi.nlm.nih.gov/pubmed/33339090
http://dx.doi.org/10.3390/polym12122996