Mutation Spectra of the MRN (MRE11, RAD50, NBS1/NBN) Break Sensor in Cancer Cells

SIMPLE SUMMARY: A DNA double strand break cuts a chromosome in two and is one of the most dangerous forms of DNA damage. Improper repair can lead to various chromosomal re-arrangements that have been detected in almost all cancer cells. A complex of three proteins (MRE11, RAD50, NBS1 or NBN) detects...

Descripción completa

Detalles Bibliográficos
Autores principales: McPherson, Matthew T., Holub, Ashton S., Husbands, Aman Y., Petreaca, Ruben C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765586/
https://www.ncbi.nlm.nih.gov/pubmed/33339169
http://dx.doi.org/10.3390/cancers12123794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765586/
https://www.ncbi.nlm.nih.gov/pubmed/33339169
http://dx.doi.org/10.3390/cancers12123794

Ejemplares similares