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Mutation Spectra of the MRN (MRE11, RAD50, NBS1/NBN) Break Sensor in Cancer Cells

SIMPLE SUMMARY: A DNA double strand break cuts a chromosome in two and is one of the most dangerous forms of DNA damage. Improper repair can lead to various chromosomal re-arrangements that have been detected in almost all cancer cells. A complex of three proteins (MRE11, RAD50, NBS1 or NBN) detects...

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Detalles Bibliográficos
Autores principales:	McPherson, Matthew T., Holub, Ashton S., Husbands, Aman Y., Petreaca, Ruben C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765586/ https://www.ncbi.nlm.nih.gov/pubmed/33339169 http://dx.doi.org/10.3390/cancers12123794

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